ÖZET
Amaç:
Çalışmamızda çocuklarda febril konvülziyon (FK) ile vitamin B12 düzeyleri arasındaki ilişkiyi değerlendirmeyi amaçladık.
Yöntem:
Çalışmaya FK ile başvuran 50 çocuk ve kontrol grubu olarak 54 sağlıklı çocuk olmak üzere 104 hasta dahil edildi. Hastaların demografik özellikleri, nöbet tipleri, biyokimyasal parametreler (glikoz, Na, K, Ca, Mg, P), enfeksiyon belirteçleri (C-reaktif protein, prokalsitonin) ve serum vitamin B12 düzeyleri hastane veri tabanından retrospektif olarak incelendi.
Bulgular:
Demografik parametreler gruplar arasında benzerdi. FK grubunda ortanca yaş 21,6±11,6 aydı. Hastaların nöbet sırasında timpanik termometre ile ölçülen ortalama ateşi 38,3±0,29 olup, hastaların %76’sı basit FK, %22’si kompleks FK ile başvurdu. Etiyolojide en sık (%72) üst solunum yolu enfeksiyonu olarak tanımlandı. FK geçiren grubun serum vitamin B12, sodyum, potasyum, kalsiyum, magnezyum, fosfor ve trombosit değerleri kontrol grubuna göre istatistiksel olarak düşüktü.
Sonuç:
Yaptığımız çalışmada, FK grubunda vitamin B12 düzeyleri, kontrol grubuna göre anlamlı olarak düşük bulunmuştur. Düşük B12 vitamini düzeylerinin artmış FK riskine katkıda bulunabileceğini düşünüyoruz.
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