Öz
Sonuç:
Çalışmamızın hematolojik bulguları, HIV pozitif bireylerde antiretroviral ilaçların ve diğer ajanların seçiminde ve ayrıca yan etkilerin gelişiminin izlenmesinde çıkarımlara sahiptir. Bu sonuçlar sosyo-ekonomik ve coğrafi farklılıklara sahip ülkeler arasında farklılık göstermektedir.
Bulgular:
Bu çalışmada en sık görülen sitopeni normositik normokromik anemi idi. Anemi, Somalili hastalarda Türk hastalara göre önemli ölçüde daha yaygındı. Somalili hastalarda ikinci sık görülen hematolojik anormallik lökopeni, Türk hastalarda ise trombositopeni idi. Türk hastalarda lökopeni nadirdi.
Yöntem:
Çalışmaya katılanların tümü, herhangi bir antiretroviral tedavi almayan, yeni teşhis edilmiş yetişkin HIV pozitif hastalardı. Dışlama kriterleri, 18 yaşından küçük olmak, hematolojik ve onkolojik bozuklukların varlığı, malignitesi olan HIV pozitif hastalar, kronik böbrek yetmezliği, karaciğer hastalığı, hamilelik, akut hastalık (yani, pnömoni veya gastroenterit), fırsatçı enfeksiyonlar ve konjenital hematolojik bozukluklar idi.
Amaç:
Sitopeni, HIV pozitif bireylerde yaygın olarak görülen ve genellikle hastalığın evresi ile ilişkili komplikasyonlardır. Sitopenilerin prevalansı HIV enfeksiyonunun evresine, cinsiyete, ırka, coğrafi konuma ve beslenme durumuna bağlıdır. Bu çalışmanın amacı etnik, coğrafi ve sosyo-ekonomik olarak farklı iki ülkede, Türkiye ve Somali’de tedavi görmemiş HIV ile enfekte hastalarda sitopeni sıklığını değerlendirmektir.
Anahtar Kelimeler: Anemi, edinsel immün yetmezlik sendromu, sitopeni, Somali, Türkiye
Kaynakça
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